Clinical Trials

Taking science forward together

WHAT IS A CLINICAL TRIAL?

A clinical trial is a research study on human participants to determine whether a treatment is safe and effective. It aims to answer three key questions:

  • Does the treatment work?
  • Does it work better than other treatments for the same condition?
  • Is it safe for different groups of patients?

Clinical trials are monitored by outside experts to safeguard participants’ health. Treatments go through several clinical trial ‘phases’ – I-IV – to track safety and effectiveness before and after being approved.

INTERVENTIONAL TRIALS

INTERVENTIONAL TRIALS

In interventional trials, participants are assigned to groups that receive either a treatment or a placebo (i.e., a ‘lookalike’ treatment that contains no actual treatment). Interventional trials allow researchers to evaluate the health and safety effects that are specifically caused by the treatment.

OBSERVATIONAL STUDIES

OBSERVATIONAL STUDIES

Observational studies do not involve providing new treatments to patients; instead, they aim to understand how participants behave in ‘real world’ settings by studying how people respond to the medications they are already taking. These studies give scientists a more realistic idea of the factors influencing patients’ health and treatment.

Phases of clinical trials

Researchers conduct clinical trials in phases, I through IV.

Why take part in a clinical trial?

Volunteers take part in clinical trials for a multitude of reasons – and participation is a very personal decision.

Learning opportunity

Participants have the opportunity to learn more about the treatment options for their condition from the medical professionals on the research team.

Greater knowledge

Through a better understanding of different measurements, participants gain information about the short- and long-term health impacts of a new treatment.

Advanced access

Participants may be able to access innovative treatments before they become widely available to the public.

Sharing insights to help others

Clinical trials can improve care for everyone by helping doctors understand and treat conditions in new ways, by improving the effectiveness of treatments, making them easier to take, or reducing their side effects.

Medical contribution

By contributing to the generation of new information in clinical trials, participants help move science forward.

FAQs

To decide whether to take part in a clinical trial you should understand why the clinical trial is being conducted and what will happen if you decide to take part. The study center will provide you with a document containing information about the trial. A member of the study staff will also explain the study and answer any questions. You can take the time to discuss with friends and family too.

You can visit Health Canada’s Clinical Trials Database. You can also talk to your healthcare provider. Clinical Trials that are sponsored by Ipsen are listed here.

The results of clinical trials that are sponsored by Ipsen are provided in lay summaries. You can also visit ClinicalTrials.gov and select the ‘results’ tab of each study to view in a tabular summary.